Pathogenesis and management of parathyroid hyperplasia in chronic renal failure: role of calcitriol
Fukagawa, M.; Kitaoka, M.; Fukuda, N.; Yi, H.; Kurokawa, K.
Mineral and Electrolyte Metabolism 21(1-3): 97-100
1995
ISSN/ISBN: 0378-0392 PMID: 7565473 Document Number: 3512
The most important point in our strategy is to prevent parathyroid hyperplasia from its early phase, thus keeping secondary hyperparathyroidism controllable by calcitriol therapy. The management should be especially focused on the prevention of the progression from typeIII to type-IV hyperparathyroidism. Thus, early use of active vitamin D [22], calcitriol pulse therapy and/or phosphorus restriction is recommended. The changes in parathyroid gland size as well as PTH hypersecretion should also be taken into account in the management of secondary hyperparathyroidism.
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