Comparison of fluconazole and ketoconazole in the therapy of vaginal candidiasis by administration in two different oral doses
Bottino, G.; Menna, C.
Minerva Ginecologica 42(5): 197-199
1990
ISSN/ISBN: 0026-4784 PMID: 2374654 Document Number: 351135
The authors examined 20 patients affected by vaginal candidiasis and evaluated the efficacy and tolerability of treatment with Fluconazole in comparison with Ketoconazole, using two different doses of oral administration: Fluconazole, 150 mg in a single dose; Ketoconazole, 400 mg/die for 5 days. There were no significant differences in results; adverse effects were insignificant and the level of efficacy, which was the same in both cases, was high. In conclusion, both molecules are confirmed to be efficacious, although patients showed a preference for the single dose and for only one day of therapy.