Fetal levels of tobramycin following maternal administration
Fernandez, H.; Bourget, P.; Delouis, C.
Obstetrics and Gynecology 76(5 Part 2): 992-994
1990
ISSN/ISBN: 0029-7844 PMID: 2216276 Document Number: 350580
A single dose of tobramycin 2 mg/kg was given intravenously to a woman who presented a 22-week heterotopic pregnancy with both intrauterine and ovarian gestations and two living fetuses. After excision of the adnexum, tobramycin levels were measured in the maternal serum and in the fetal fluids and tissues. Antibiotic levels were especially high in the fetal spleen and kidney.
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