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In vitro antibacterial activity of cefotaxime and desacetylcefotaxime, alone or in combination, against gram-positive cocci

Cruciani, M.; Navarra, A.; Di Perri, G.; Danzi, M.C.; Concia, E.; Bassetti, D.

Drugs under Experimental and Clinical Research 16(11): 565-568

1990

ISSN/ISBN: 0378-6501
PMID: 2101779
Document Number: 350270
The in vitro activity of cefotaxime and desacetylcefotaxime against Staphylococcus aureus, Staph. epidermidis and Streptococcus pyogenes was investigated. Synergy studies were performed using time-kill curves and the chequerboard test. The time-kill curves were performed on five strains each of Staph. aureus, Staph. epidermidis and Strep. pyogenes; cefotaxime and desacetylcefotaxime were tested alone or in combination at MIC and sub-MIC values. The chequerboard test was performed in microtitre plates on ten strains each of Staph. aureus, Staph. epidermidis and Strep. pyogenes: the results were interpreted by the fractional inhibitory concentration index. In some cases both methods showed synergistic interaction against the staphylococci tested. Indifference was observed against Strep. pyogenes.

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Garcia Arribas, M.L.; de la Rosa Jorge, M.C.; Mosso Romeo, M.A. 1983: Characterization and antibacterial sensitivity of strains of Gram-positive cocci isolated from orally administered solid drugs Journal de Pharmacie de Belgique 38(3): 140-146
Maccanti, O.; Bonadio, M. 1992: Activity of vancomycin against recently isolated nosocomial gram-positive cocci Drugs under Experimental and Clinical Research 18(7): 295-297
Klietmann, W.; Focht, J.; Nösner, K. 1987: Comparative in vitro study of the antibacterial effect of cefotetan against gram-positive and gram-negative aerobic and anaerobic strains from fresh clinical isolates Chemioterapia: International Journal of the Mediterranean Society of ChemoTherapy 6(2 Suppl): 92-93
Boisivon, A.; Perenet, F.; Guiomar, C. 1989: Sensitivity of cefatrizine on clinical isolates of gram-positive, gram-negative cocci, Haemophilus, and Enterobacteriaceae Journal of ChemoTherapy 1(4 Suppl): 304-305
Moros, M.; Coll, R.; Esteve, M.; Parés, J.; Xicota, M.A. 1987: In vitro activity of E-3846, a new fluoroquinolone, against gram-negative and gram-positive bacteria Chemioterapia: International Journal of the Mediterranean Society of ChemoTherapy 6(2 Suppl): 149-151
Moore, E.S.; Jimenez, M.; Barriere, S.L.; Cimino, M.L.; Fekety, F.R. 1988: Additive and synergistic bactericidal activity contributed by desacetylcefotaxime during cefotaxime therapy Clinical Pharmacy 7(12): 901-905
Bastianini, L.; Sposini, T.; Bartoli, A.; Marconi, P. 1988: Comparative in vitro activity of imipenem against gram-positive and gram-negative aerobic bacteria from clinical isolates Microbiologica 11(2): 137-142
Rouhan, D.; Le Noc, P.; Le Noc, D. 1986: In-vitro activity of ceftriaxone on Gram-negative bacilli with various resistance phenotypes to cephalosporins. Comparison with cefotaxime, cefmenoxime, moxalactam, ceftazidime Pathologie-Biologie 34(5): 404-409
Nitsche-Schmitz, D.P.; Rohde, M.; Chhatwal, G.S. 2007: Invasion mechanisms of Gram-positive pathogenic cocci Thrombosis and Haemostasis 98(3): 488-496
Szczerba, I. 2005: Gram-positive cocci as an opportunistic infection factor Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego 18(106): 462-464
Dorobăţ, O.M.; Bădicuţ, I.; Tălăpan, D.; Tenea, C.; Rafila, A. 2010: Antibiotic resistance of Gram-positive cocci isolated in 2008 Bacteriologia Virusologia Parazitologia Epidemiologia 55(2): 83-92
Canepari, P.; Fontana, R.; Satta, G. 1991: New targets for the mechanism of action of antibiotics active against gram-positive cocci Journal of ChemoTherapy 3(Suppl 1): 141-143
Papadopoulou, B.; Courvalin, P. 1988: Dispersal in Campylobacter spp. of aphA-3, a kanamycin resistance determinant from gram-positive cocci Antimicrobial Agents and Chemotherapy 32(6): 945-948
Gogov, I.; Bonovska, M.; Koleva, P. 1981: DNA nucleotide composition of Gram-positive cocci isolated from food products of animal origin Veterinarno-Meditsinski Nauki 18(10): 41-45
Piccolomini, R.; Di Sipio, L.; Ravagnan, G. 1980: Evaluation of the antibacterial activity in vitro of various cephalosporins on different gram-negative bacterial species of recent clinical isolation Bollettino della Societa Italiana di Biologia Sperimentale 56(2): 133-139
Leclercq, R.; Bauduret, F.; Soussy, C.J. 1989: Selection of constitutive mutants of gram-positive cocci inducible resistant to macrolides, lincosamides and streptogramins (MLS): comparison of the selective effects of the MLS Pathologie-Biologie 37(5 Pt 2): 568-572
Rodríguez, J.L.; Vázquez, G.J.; Bermúdez, M.; De Orbeta, J.; García, Y.; Rivera, Y.; Robledo, I.E. 2002: Prospective study using standardized methodology for antimicrobial susceptibility of gram-positive cocci isolated from the Puerto Rico Medical Center Puerto Rico Health Sciences Journal 21(4): 343-347
Marks, M.I. 1975: In vitro activity of clindamycin and other antimicrobials against gram-positive bacteria and Hemophilus influenzae Canadian Medical Association Journal 112(2): 170-173
Vázquez, G.J.; Robledo, I.E.; Arroyo, A.; Nadal, E.; Rodríguez, Rés.; Bermudez, M.; Colón, M. 2003: A comparison of the antimicrobial resistance patterns of gram-positive cocci isolated from community-private and university-affiliated hospitals from Puerto Rico Puerto Rico Health Sciences Journal 22(2): 131-136
Newman, S.S.; Roy, A.F.; Luther, D.G.; Hoskins, J.D.; Cox, H.U.; Kearney, M.T. 1985: Comparative evaluation of a commercial microdilution method and a conventional disk diffusion method for determination of antibiograms of gram-positive cocci American Journal of Veterinary Research 46(1): 294-297