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Comparative evaluation of a commercial microdilution method and a conventional disk diffusion method for determination of antibiograms of gram-positive cocci

Newman, S.S.; Roy, A.F.; Luther, D.G.; Hoskins, J.D.; Cox, H.U.; Kearney, M.T.

American Journal of Veterinary Research 46(1): 294-297

1985

ISSN/ISBN: 0002-9645
PMID: 3918490
Document Number: 263131
A commercial broth microdilution system was compared with a standardized disk agar-diffusion method by testing 254 clinical strains of staphylococci and streptococci from several species of animals. A total of 2794 parallel determinations were made with 92.3% agreement between the 2 methods; of the discrepancies encountered, 3% were minor, 2.5% were major, and 2% were considerable. Consequently the commercial microdilution system can provide a reliable quantitative test for sensitivity to antimicrobials.

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