Effects of chorionic gonadotropin (hCG) therapy on the immune system
Maghnie, M.; Valtorta, A.; Moretta, A.; Priora, C.; Preti, P.
Medicina 10(2): 148-149
1990
ISSN/ISBN: 0392-6516 PMID: 1980332 Document Number: 349053
Humoral and cellular immunologic parameters were evaluated in 13 prepuberal cryptorchid boys before, during and 3 months after hCG therapy. Before treatment, all the immunologic parameters were normal except for a higher percentage of T suppressor-cytotoxic cells (CD8+). During therapy, the percentage of CD8+ cells and lymphocyte response to ConA significantly decreased, and returned to the control level after hCG withdrawal. The possible effects of long-term hCG treatment on the immune system remains to be determined.