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Immunogenic and protective properties of outer membrane proteins of Hafnia alvei

Witkowska, D.; Czarny, A.; Mulczyk, M.

Archivum Immunologiae et Therapiae Experimentalis 38(5-6): 387-393

1990

ISSN/ISBN: 0004-069X
PMID: 2130804
Document Number: 349014
Outer membrane proteins (OMP) extracted from antigenically distinct or related strains of Hafnia alvei containing defined composition of major proteins proved to be immunogenic. Intraperitoneal immunization of mice with a single dose of such preparations protected the animals against homologous and heterologous Hafnia strains. The OMP preparations were also found to induce protection with varying intensity against Escherichia, Proteus, Shigella and Salmonella.

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