The forensic chemical determination of antidiabetic agents
Muzhanovskiĭ, E.B.; Fartushnyĭ, A.F.; Sukhin, A.P.; Sedov, A.I.
Sudebno-Meditsinskaia Ekspertiza 33(2): 38-40
1990
ISSN/ISBN: 0039-4521 PMID: 2396290 Document Number: 348913
Method of detection, purification and determination of some antidiabetic agents (ADA)--bucarban, butamid, glybenclamid, glybutide, methformine, prediane, chlorpropamide, chlocyclamide, cyclamide in biological material was developed. Microcrystalline reaction with 10% alcoholic potassium iodide, colour reactions and investigation by TLC method both native substances and nitration products were developed to identify ADA. The assay is performed by spectrophotometry. Detection limit is 2-5 mg of each substance in 50 g of the material.