Acute pancreatitis and reduction of H+ ion concentration in gastric secretions in experimental acute myocarditis produced by Indian red scorpion, Buthus tamulus, venom

Murthy, K.R.; Medh, J.D.; Dave, B.N.; Vakil, Y.E.; Billimoria, F.R.

Indian Journal of Experimental Biology 27(3): 242-244

1989


ISSN/ISBN: 0019-5189
PMID: 2606531
Document Number: 347300
Crude venom (4 mg/kg) of the scorpion B. tamulus [Buthotus tamulus] was given in saline to anaesthetized dogs and rabbits. It produced a reduction in gastric H+ ion concentration in dogs with venom-caused acute myocarditis. Simultaneously, an increase in circulating amylase and lipase level was also observed. However 60% of the venom-poisoned rabbits showed an elevated lipase level without a parallel increase in amylase. It is suggested that the venom acts directly on exocrine secretions from the pancreas to cause acute pancreatitis.

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