Respiratory depression following controlled-release morphine sulfate tablets
Hoogslag, P.A.; van Dijk, B.; Vinks, A.A.
Nederlands Tijdschrift Voor Geneeskunde 133(10): 516-517
1989
ISSN/ISBN: 0028-2162 PMID: 2710234 Document Number: 347077
Controlled release morphine sulfate (MS Contin) is a relatively new oral preparation for the relief of chronic severe (cancer) pain. We describe a patient with severe neuralgia who experienced respiratory depression after ingestion of one single dose of morphine sulfate (20 mg). Administration of nalorphine chloride resulted in instant normalisation of respiratory function. This case illustrates respiratory depression as an adverse effect of MS Contin.
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