EEG findings during the course of HIV infection
Schnurbus, R.; Könneke, J.; Friedrich-Jännicke, B.; Flessenkämper, S.; Bienzle, U.; Girke, W.
Eeg-Emg Zeitschrift für Elektroenzephalographie Elektromyographie und verwandte Gebiete 20(4): 238-242
1989
ISSN/ISBN: 0012-7590 PMID: 2514082 Document Number: 346916
Clinical neurological complications in HIV-infection (Human Immunodeficiency Virus) are seen in later stages of the disease. EEGs of 186 patients in different stages of HIV-infection and of 44 HIV-seronegative volunteers (total of 566 recordings) were evaluated visually; this revealed an increasing appearance of CNS-dysfunction (slowing of background activity, focal and diffuse CNS-dysfunction) associated with a progression of the disease. Slowing of background activity was already found in early stages of HIV-infection. Additional focal and diffuse changes in the electrical activity of the brain are also seen with progression of the infection (LAS/ARC-AIDS). The correlation between these electroencephalographic changes and HIV related clinical symptoms are non specific however, EEG recordings can be a valuable aid in following CNS-dysfunction during the course of HIV-infection.