Acute reversible renal insufficiency during treatment with diclofenac
Cicuttini, L.; Colatutto, A.; Pellegrini, M.A.; Rotolo, V.
La Clinica Terapeutica 128(2): 81-86
1989
ISSN/ISBN: 0009-9074 PMID: 2523777 Document Number: 345717
The authors, after a brief discussion of the main effects of the prostaglandins on renal blood flow, report a case of acute renal failure following the ingestion of diclofenac. Although there is little doubt that diclofenac is among the safest NSAIDs the Authors consider that caution is still necessary, especially in the treatment of older and dehydrated patients.