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What is the contribution of yeast genetics to tumor biology and tumor diagnosis?

Breitenbach, M.; Achatz, G.; Heger, S.; Hufnagl, P.; Wallner, J.; Eichler, M.; Spevak, W.; Schweiger, C.; Rumpold, H.

Wiener Klinische Wochenschrift 101(15): 495-504

1989

ISSN/ISBN: 0043-5325
PMID: 2672609
Document Number: 344686
This short review article discusses methods and results of oncogene research in yeast. Current knowledge of the sequence, expression and biological function of ras-homologous genes of the yeast Saccharomyces cerevisiae is presented, as well as the implications of these findings for oncogene research in mammals. We review recent examples of highly conserved eukaryotic genes involved in growth control and mitosis control, including recent work from our own laboratories.

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