The TRH test using the Bulgarian preparation Protilerin in the diagnosis of hyperthyroidism
Manolov, D.; Zakharieva, B.; Lazarov, G.; Manov, A.; Vŭrbanov, V.
Vutreshni Bolesti 28(5): 30-33
1989
ISSN/ISBN: 0506-2772 PMID: 2515659 Document Number: 344150
The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stimulation. All patients with hyperthyroidism showed a suppressed response to the stimulation. In two of the patients with euthyroid infiltrative ophthalmopathy the response was similar to that of the healthy controls. The Bulgarian drug Protilerin is suitable for the performance of the TRH test in the diagnosis of hyperthyroidism.