Efficacy and safety of antihistamines and expectorants in nonprescription cough and cold preparations
Hendeles, L.
PharmacoTherapy 13(2): 154-158
1993
ISSN/ISBN: 0277-0008 PMID: 8097037 Document Number: 3440
In conclusion, it is clear to me from reviewing this data that antihistamines and expectorants provide no measurable relief for patients suffering from the common cold. Since antihistamines have the potential to cause harmful effects, the risks associated with their use outweigh any meager benefit. It is my opinion that these drugs should be removed from all nonprescription products promoted for the relief of cough and cold symptoms. This recommendation, of course, does not apply to products promoted solely for the relief of allergy symptoms.
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