Effectiveness of antihistamines in common cold
Sakchainanont, B.; Ruangkanchanasetr, S.; Chantarojanasiri, T.; Tapasart, C.; Suwanjutha, S.
Journal of the Medical Association of Thailand 73(2): 96-101
1990
ISSN/ISBN: 0125-2208 PMID: 1972174 Document Number: 3439
There is no beneficial effect of treating the common cold with antihistamines than placebo, except when the child has copious nasal discharge. Clemastine improved the character of nasal discharge significantly. Side effects, e.g. sedation, in antihistamine treated groups were not different from the placebo group. Should antihistamine be indicated, clemastine fumarate may be appropriate for patients who have low compliance or have to go to school. Since it is a long-acting antihistamine, it is more convenient for patients, with a twice daily dosage. However, the daily cost of clemastine is slightly higher than chlorpheniramine maleate.
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