The diagnosis of hypertension (research on kidney biopsies and microalbuminuria
Arabidze, G.G.; Sokolova, R.I.; Titov, V.N.; Tarasov, A.V.
Terapevticheskii Arkhiv 61(9): 8-12
1989
ISSN/ISBN: 0040-3660 PMID: 2688163 Document Number: 343202
Patients with essential hypertension, hypertonic glomerulonephritis and Conn's syndrome were examined for excretion of albumin, immunoglobulin G and beta 2-microglobulin. The results obtained were correlated with pathological changes in liver parenchyma according to biopsies withdrawn from the patients. Essential hypertension running a benign course was not characterized by pronounced changes in excretion of the above proteins. Injury to the glomerular apparatus of the kidneys in glomerulonephritis was attended by considerable rise of albumin and immunoglobulin excretion whereas injury to the tubular structures by the increase of beta 2-microglobulin excretion. It is suggested that analysis of microalbuminuria can be used in the differential diagnosis of arterial hypertension running its course in association with the minor urinary syndrome.