Problem of typological differentiation of the defect in symptom-poor schizophrenia (clinico-genetic correlations)
Lu'kianova, L.L.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 89(10): 92-98
1989
ISSN/ISBN: 0044-4588 PMID: 2618242 Document Number: 340728
The clinico-genealogical method with the use of a genetic-mathematic analysis was applied to examine 85 probands with pure-symptoms schizophrenia (221 relations of grade I kinship). Schizophrenia with the defect of the simple deficiency type was established to be genetically, similar to schizophrenia with a psychopath-like defect characterized by veschroben. Different types of familial predisposition by the type of schizophrenia+ and by the spectrum of psychopathies were found to correspond to the studied variants of pure-symptoms schizophrenia. These correlations were confirmed by the data of the genetic-correlation analysis. It is assumed that determination of the typological differences in the defect structure in pure-symptoms schizophrenia is under the control of constitutional and genetic factors.