Theophylline poisoning in childhood: depurative therapy using a combination of activated charcoal and a saline cathartic
Chiossi, M.; Rosati, U.; Renna, S.; Lattere, M.; De Santis, L.
Minerva Pediatrica 41(10): 535-537
1989
ISSN/ISBN: 0026-4946 PMID: 2615728 Document Number: 340727
The Authors describe two cases of theophylline poisoning and discuss advantages of activated charcoal and magnesium hydroxide therapy. This treatment seems to be better in patients for whom hemoperfusion could be delayed. In fact, activated charcoal can determine a real decrease in serum theophylline as experimental data show. Patients who overdose with slow release theophylline preparation should receive multiple oral doses of activated charcoal; they should also receive multiple oral doses of cathartic, both saline or sorbitol like. There is a lack of references about the activated charcoal plus magnesium hydroxide regimen particularly in childhood. The Authors discuss their own experience.