Application of preoperative chemotherapy to postoperative chemotherapy in malignant bone and soft tissue tumors
Furuse, K.; Morimoto, K.; Yamamoto, K.; Orito, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 16(4 Pt 2-3): 1749-1754
1989
ISSN/ISBN: 0385-0684 PMID: 2730070 Document Number: 339266
We analyzed the effectiveness of preoperative chemotherapy mainly with radiographic images in 9 patients with osteosarcoma, 5 patients with other malignant bone tumor and 14 patients with malignant soft tissue tumor. Judging from the application of preoperative to postoperative chemotherapy and outcome, its evaluation was useful in osteosarcoma and malignant soft tissue tumors. Changes in radiographic images by preoperative chemotherapy were the same in malignant bone and soft tissue tumors, but the reactivity of the latter was more evident. In malignant bone and soft tissue tumors, the effects of preoperative chemotherapy should be evaluated for the cases with resection of primary tumor. Malignant bone tumors excepting osteosarcoma also should be assessed through further accumulation of many more cases.