Antibiotic use in the elderly. a selective review
Gleckman, R.A.
Infectious Disease Clinics of North America 3(3): 507-516
1989
ISSN/ISBN: 0891-5520 PMID: 2671136 Document Number: 338968
There are unique challenges for the physician who prescribes an antibiotic to an elderly patient. Advanced age is associated with physiological alterations and a reduction in the excretion of numerous compounds. Mental and physical illness in aged patients will impair unsupervised drug compliance. Antibiotic-related adverse events and antibiotic-associated drug interactions pose a threat to life and impede the desired therapeutic outcome.