Pathogenesis of phantom limb syndrome and its treatment
Naryshkin, A.G.; Gurchin, F.A.; Samoĭlov, K.A.; Kirsanova, G.V.; Vasilevskaia, L.S.; Shvets, I.M.
Vestnik Khirurgii Imeni I. I. Grekova 144(8): 50-53
1989
ISSN/ISBN: 0042-4625 PMID: 2603307 Document Number: 338668
The spinal mechanism of the phantom pain origin is proved. The underlying factors are: segmentary spinal denervation hypersensitivity and attenuation of the descending inhibitory influence. The pathogenetic treatment of phantom pains is proposed by means of an associated treatment by GABA-ergic drug--Baclofen and alpha-2--adrenomimetic--Clofelin. Good effects of the proposed scheme of treatment confirm the correctness of the presented ideas of pathogenesis of phantom pains.