Technical artifacts in biopsy of the oral cavity. I. Clinical and histopathologic aspects
Lolli, R.; Venezia, A.; Bellardini, M.; De Nisi, S.; Demuro, G.
Minerva Stomatologica 38(1): 37-45
1989
ISSN/ISBN: 0026-4970 PMID: 2651870 Document Number: 338601
In the present work the problems of artifacts introduced in human oral biopsy specimens are discussed. The circumstances that can result in artifacts include: errors by the surgeon or assistant in handling the tissue at the time of biopsy, an improper fixation and faulty tissue processing. Different types of artifacts are described and illustrated and clinical and technical suggestions are given to prevent alterations of normal morphologic and cytologic features that can compromise an accurate diagnosis.