Anti-thyroid peroxidase antibody activity in sera of patients with systemic lupus erythematosus
Kohno, Y.; Naito, N.; Saito, K.; Hoshioka, A.; Niimi, H.; Nakajima, H.; Hosoya, T.
Clinical and Experimental Immunology 75(2): 217-221
1989
ISSN/ISBN: 0009-9104 PMID: 2702776 Document Number: 337319
Although patients with SLE have autoantibodies to thyroid peroxidase (TPO), IgG from sera of SLE patients does not inhibit TPO activities, in contrast with IgG from sera of patients with thyroid disorders. This finding suggests that the specificities of anti-TPO autoantibodies in SLE are different from those in cases of thyroid disorders. These autoantibodies to TPO should be considered when searching for associations between SLE and autoimmune thyroid disorders.