Lyophilized homologous bone grafts in middle ear surgery: new perspectives
Maisin, J.P.; Munting, E.; Delloye, C.; Gersdorff, M.
Revue de Laryngologie - Otologie - Rhinologie 110(5): 495-497
1989
ISSN/ISBN: 0035-1334 PMID: 2633256 Document Number: 336980
The authors share their experience of the use of allografts in the reconstruction of the tympano-ossicular chain. The implants were cut from the cortical substance of the long bone in patients deceased for a maximum of six hours; the donors were tested for syphilis, hepatitis, AIDS, systemic diseases or a neoplasm. These bone allografts were cut to size, degreased, demineralized, frozen and then lyophilized in order to be presented to the surgeon in a sterile container (Bone Bank). The implants were all tolerated well. The anatomical results were satisfactory. Optical microscopic studies showed that the implant was: a) covered with mucosa, b) full of osteoblasts and c) the site of a bone neoformation. Experimental research is currently underway in order to perfect the implant preparation methodology.