An epidemiological survey of goiter caused by excessive iodine in potable water in Cangzhou region
Zheng, H.B.
Zhonghua Yu Fang Yi Xue Za Zhi 23(5): 305-307
1989
ISSN/ISBN: 0253-9624 PMID: 2625069 Document Number: 336746
This article describes a relationship between iodine and function and shape of thyroid gland. There was positive correlation between the prevalence rate of goiter and iodine content in drinking water [ln (10x)] and urine [ln (5x)]. Their curve fitting regression equations were y = 36.36 - 10.94 x + 0.83x2 and y = 22.39 - 6.36 x + 0.48x2 respectively. Use 3 per cent as criterion of disease area, threshold upper limit value of water and urinary iodine content should be 400 micrograms/L and 890 micrograms/gCr respectively.