Effect of blood transfusions on the survival of patients with colorectal cancers
Klingler, K.; Zhang, X.; Menghini, T.; Metzger, U.; Largiadèr, F.
Helvetica Chirurgica Acta 55(5): 685-688
1989
ISSN/ISBN: 0018-0181 PMID: 2715032 Document Number: 334771
Blood transfusion is reported to cause immunosuppression. An adverse relationship between perioperative blood transfusions and the risk of subsequent recurrence of cancer was reported recently. We reviewed the records of 282 patients and analyzed the interaction between blood tranfusion and the outcome of Dukes stages A, B and C colorectal cancers treated by radical resection during the years 1978-1985. 53 of these patients did not receive any blood transfusions. The actuarial survival analysis (Cutler and Ederer) showed no significant difference for the overall and recurrence-free survival. This study did not support the hypothesis that blood transfusions had an adverse effect on survival of patients with colorectal cancer.