Comparison of the action of 2 effective analgesics. Experimental study: tramadol versus tilidine/naloxone
Bromm, B.; Herrmann, W.M.; Scharein, E.
Fortschritte der Medizin 107(17): 385-389
1989
ISSN/ISBN: 0015-8178 PMID: 2663681 Document Number: 332183
In the present study involving healthy test subjects, tilidin/naloxone (Valoron N; VAL) proved to have an analgesic effect roughly twice as pronounced as that of tramadol (TRA). Moreover, the analgesic effect of VAL showed a significantly more rapid onset than did that of TRA. This finding reflects the difference in rate of action of the active substances. In accordance with these findings, VAL is thus the most powerful analgesic presently available on the German market on simple prescription.