Characteristics of cellular immunity in multiple sclerosis
Demina, T.L.; Boĭko, A.N.; Balashov, K.E.; Pinegin, B.V.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 89(2): 35-41
1989
ISSN/ISBN: 0044-4588 PMID: 2524943 Document Number: 331549
In 30 patients with definite multiple sclerosis a combined clinicoimmunological investigation was performed. The results of estimation of T-lymphocyte subpopulaitons by means of flow cytometry and monoclonal antibodies; of proliferative responses to PHA, PWM and Con A, to PHA with autoserum; of synthesis and reception of IL-2 containing material is discussed. A hypothesis of a cyclic course of the immunopathologic process is suggested (autoimmune and immunodeficiency stages).