Determination of immunologic parameters in patients with lung tuberculoses of various stages with special reference to serum IgE concentration
Greinert, U.; Ernst, M.; Haas, H.; Schlaak, M.
Pneumologie 43(5): 254-258
1989
ISSN/ISBN: 0934-8387 PMID: 2740305 Document Number: 329045
In patients with lung tuberculosis--depending on the severity of the disease--delayed-type hypersensitivity reaction is weakened, also in cases of non-miliary tuberculosis. On analysing the mononuclear cells of peripheral blood, abnormalities are found, in particular an increase in the monocyte count. In addition to increasing levels of serum immunoglobulin A and G, circulating immune complexes were detected in 50% of the patients. In 50% of the patients we found elevated IgE-serum levels, which decreased in response to treatment but did not return to normal.