Effect of indomethacin and vasotocin on oviposition in the hen (Gallus domesticus)
Rzasa, J.; Paczoska-Eliasiewicz, H.
Acta Physiologica Polonica 40(1): 111-115
1989
ISSN/ISBN: 0044-6033 PMID: 2603742 Document Number: 328978
The interrelationship between prostaglandins (PG) and vasotocin (AVT) in the oviposition of the domestic hen was investigated. Single or combined injections of indomethacin (IND), an inhibitor of PG synthesis, and AVT gave delay or induction of oviposition. Injection (i.m.) of IND (5 mg/kg) 5 h before oviposition resulted in 15.1 h (+/- 0.93) delay of oviposition. Injection (i.v.) of AVT (0.1 microgram/kg) 2.5 h before oviposition caused premature oviposition within a few minutes (3.1 +/- 0.2). Combined injection of IND and AVT at 5 h and 2.5 h, respectively, before oviposition caused the delay of oviposition (15.8 h +/- 0.8). The results indicate that IND blocked the induction of oviposition by AVT.