Synovial fluid changes in mycoplasma induced septicaemic polyarthritis of goat kids
Nayak, N.C.; Bhowmik, M.K.
Indian Journal of Experimental Biology 27(12): 1071-1073
1989
ISSN/ISBN: 0019-5189 PMID: 2633969 Document Number: 328341
Synovial fluid samples of goat kids inoculated (ip) with 5 ml of 48 hr log phase culture of Mycoplasma mycoides sub. sp. mycoides (large colony type) containing 107 cfu/ml were analysed for physical, cytological and biochemical properties. The synovial effusions were exudative in nature with increased volume. Gross appearances were serofibrinous, haemorrhagic and turbid containing flocculent materials with immediate clot formation. Mucinous precipitate quality was very poor having friable precipitates with cloudy supernatant. There were high total leycocytic and erythrocytic counts with significant high numbers of both neutrophils and lymphocytes. Synovial fluid sugar contents were significantly reduced, whereas total protein contents were significantly increased with concomitant reduction in albumin: globulin ratio. The alkaline phosphatase and transaminase values were also markedly increased in the synovial fluids of mycoplasma induced polyarthritic goat kids. The results may provide a chemical guideline for diagnosis, chemotherapy and prognosis of different joint diseases in domesticated animals.