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Distribution and metabolism of azoxybenzene in the rat

Kujawa, M.; Macholz, R.; Härtig, M.; Plass, R.; Nickel, B.

Zeitschrift für die Gesamte Hygiene und Ihre Grenzgebiete 35(5): 255-257

1989

ISSN/ISBN: 0049-8610
PMID: 2750228
Document Number: 327851
No sex differences could been shown after absorption and distribution of azoxybenzen in the rat. The highest level occur in the thyroid gland, the adrenals and in the fat tissues. The maximum level was reached 30 min. after application. Azoxybenzen is degraded via azobenzene hydrazobenzene and aniline. The main pathway leds to the formation of 2-hydroxyazobenzen.

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