Neutropenias in children
Veber, F.; Fischer, A.; Coulombel, L.; Griscelli, C.
Annales de Pediatrie 36(6): 365-373
1989
ISSN/ISBN: 0066-2097 PMID: 2667426 Document Number: 327706
Whereas the clinical expression of childhood neutropenias is fairly uniform, consisting mainly in infections, a wide variety of etiologies may be involved. Pathophysiologic mechanisms have not all been completely elucidated. We review the different etiologies of neutropenia in children using the classification that we believe is the most helpful to clinicians. The clinical features and management of primary chronic neutropenias are described in detail. On the basis of our experience we suggest a practical diagnostic strategy for investigating children with neutropenia.