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Hemostasis and T-cell immunity in lung cancer patients

Moiseev, S.I.; Kravtsova, V.M.; Efimov, K.V.; Evtiukhin, A.I.; Afanas'ev, B.V.

Voprosy Onkologii 35(11): 1305-1310

1989

ISSN/ISBN: 0507-3758
PMID: 2609518
Document Number: 327659
Complex examination of hemostatic system and T-cell-mediated immunity in 19 cases of stage II-IV lung cancer showed an increased activity of blood coagulation system to be associated with a decrease in OKT3+, OKT11+ and OKT4+ T-lymphocyte subsets levels. A reverse correlation was established between plasma--Willebrand's factor level and those of OKTè+ and OKT8+ lymphocytes whereas a direct one--between blood-platelet aggregate level and that of OKT4+. The data obtained emphasized the need to consider the status of hemostatic system when evaluating the function of cell-mediated immunity.

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