Clinical significance of the immunocompetence of patients with acute leukemia in the remission phase

Shalaev, V.A.; Gushcha, A.A.; Shalaev, V.A; Gushcha, A.A

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Clinical significance of the immunocompetence of patients with acute leukemia in the remission phase

Shalaev, V.A.; Gushcha, A.A.

Gematologiia i Transfuziologiia 34(4): 27-30

1989

ISSN/ISBN: 0234-5730

PMID: 2744377

Document Number: 327645

During 6 months of a remission, the distribution of lymphocyte subpopulations was similar in 18 patients with a short-term (5.7 +/- 0.7 months) remission and in 15 patients with protracted remissions (36.4 +/- 5.7 months). One to three months prior to the development of a relapse there was a significant drop of the amount of immunoregulating T lymphocytes and B cells as compared with their amount within the first 6 months of a remission. This makes it possible to form a risk group which may develop relapses within the nearest 3 months, with a probability being equal to 60-75 percent.