Overview of patient compliance with medication dosing: a literature review
Greenberg, R.N.
Clinical Therapeutics 6(5): 592-599
1984
ISSN/ISBN: 0149-2918 PMID: 6383611 Document Number: 3276
The literature was reviewed in an effort to relate frequency of dosing and other influences with patient compliance in medication taking. Once-a-day and twice-a-day regimens were associated with significantly better compliance (73% and 70%, respectively) than were three-times-daily (52%) and four-times-daily (42%) regimens. Compliance is not related to income, social class, occupation, or educational background, and it cannot be accurately predicted by physicians. Unintentional errors in taking medication are made by 50% to 90% of patients.
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