Synthesis of new linearly annulated tricycles as rigid dopamine congeners
Perrone, R.; Berardi, F.; Bettoni, G.; Tortorella, V.
Il Farmaco; Edizione Scientifica 43(1): 71-77
1988
ISSN/ISBN: 0430-0920 PMID: 3396690 Document Number: 326380
A simple synthetic route that leads to three isosters of octahydrobenzoquinoxaline (VIII c) respectively is here reported. These compounds can be considered as new structural models of dopamine agonists.
Document emailed within 1 workday
Related Documents
Perrone, R.; Berardi, F.; Bettoni, G.; Tortorella, V. 1988: Dopamine receptor agonists: new angularly annulated tricyclic compounds Il Farmaco; Edizione Scientifica 43(1): 61-69Dragović, D.; Soskić, V.; Joksimović, J. 1995: Synthesis and evaluation of N,N-di-n-propyl-5,6,7,8-tetrahydro-1 H-benz[f]benzimidazol-6-yl-amine and related congeners as dopaminergic ligands Die Pharmazie 50(10): 678-680
Parker, E.M.; Cubeddu, L.X. 1986: Effects of d-amphetamine and dopamine synthesis inhibitors on dopamine and acetylcholine neurotransmission in the striatum. I. Release in the absence of vesicular transmitter stores Journal of Pharmacology and Experimental Therapeutics 237(1): 179-192
Gronowitz, S.; Svensson, L.; Herslöf, M.; Karlsson, O. 1979: Thiophene-containing potentially neuroleptic rigid spiroamines. I. on the synthesis and metalation of some benzocycloheptathiophenes Acta Pharmaceutica Suecica 16(6): 353-364
Ceccarelli, S.; D'Alessandro, A.; Magnante, F.; Scuri, R.; Zanarella, S. 1993: Synthesis and A1-adenosine receptors affinities of purino[7,8-c]quinazoline-8,10(9H,11H)-diones as rigid analogues of 8-arylxanthines Farmaco 48(9): 1301-1312
Gronowitz, S.; Svensson, L.; Stjernström, N.; Ogren, S.O. 1979: Thiophene-containing potentially neuroleptic rigid spiroamines. II. Synthesis of some N,N-dimethylamino-substituted spiro[H-cyclohepta[2,1-b;4,5-b]dithiophene-9,1'-cycloalkanes Acta Pharmaceutica Suecica 16(6): 365-375
Aretha, C.W.; Sinha, A.; Galloway, M.P. 1995: Dopamine D3-preferring ligands act at synthesis modulating autoreceptors Journal of Pharmacology and Experimental Therapeutics 274(2): 609-613
Sugi, H. 1971: Local activation of crayfish phasic and tonic muscle fibres with linearly rising currents Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan 33(9): 597-598
Görlitzer, K.; Trittmacher, J.; Bartke, U. 2002: Bis(lactone)-annulated 4H-pyranes and 1,4-dihydropyridines from 3,3'-(nitrobenzlidene)-bistetronic acids Die Pharmazie 57(9): 606-609
Booth, R.G.; Baldessarini, R.J.; Kula, N.S.; Gao, Y.; Zong, R.; Neumeyer, J.L. 1990: Presynaptic inhibition of dopamine synthesis in rat striatal tissue by enantiomeric mono- and dihydroxyaporphines Molecular Pharmacology 38(1): 92-101
Raevskiĭ, K.S.; Shemanov, A.I.; Kudrin, V.S. 1982: Des-1-tyrosine-gamma-endorphin: an assessment of its neuroleptic properties and effect on dopamine synthesis Farmakologiia i Toksikologiia 45(5): 5-8
Biggio, G.; Casu, M.; Klimek, V.; Gessa, G.L. 1980: Dopamine synthesis: tolerance to haloperidol and supersensitivity to apomorphine depend on presynaptic receptors Advances in Biochemical Psychopharmacology 24: 17-22
Stock, G.; Kummer, P.; Steinbrenner, J. 1980: Long-term application of haloperidol: effect of anticholinergic treatment on the rate of dopamine synthesis Advances in Biochemical Psychopharmacology 24: 291-294
Sedvall, G.; Nybäck, H. 1973: Effect of clozapine and some other antipsychotic agents on synthesis and turnover of dopamine formed from 14C-tyrosine in mouse brain Israel Journal of Medical Sciences 9 Suppl: 24-30
Schmidt, C.J.; Taylor, V.L.; Abbate, G.M.; Nieduzak, T.R. 1991: 5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa Journal of Pharmacology and Experimental Therapeutics 256(1): 230-235
Galloway, M.P.; Wolf, M.E.; Roth, R.H. 1986: Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: studies in vivo Journal of Pharmacology and Experimental Therapeutics 236(3): 689-698
Riffee, W.H.; Gerald, M.C. 1976: Determination of endogenous concentrations of norepinephrine and dopamine and their rates of synthesis in a single mouse brain: biphasic effects of (+)-amphetamine Archives Internationales de Pharmacodynamie et de Therapie 219(1): 70-78
Li, G.-c.; Zhang, B.-l.; Xia, J.-y.; Fang, Z.-J. 2015: Synthesis and receptor binding assay of indolin-2-one derivatives as dopamine D4 receptor ligands Die Pharmazie 70(8): 511-514
Pinnock, C.B.; Alderman, C.P. 1992: The potential for teratogenicity of vitamin a and its congeners Medical Journal of Australia 157(11-12): 804-809
Stell, J.G.; Thomas, S.E. 1972: The effect of chloroquine and its congeners on mitochondrial oxidation Journal of Pharmacy and Pharmacology 24(Suppl): 163p-164