Comparative study of various technics for the determination of human serum galactosyltransferase

Bar, E.; Malas, J.P.; Gauduchon, P.; Aubert, M.; Sichel, F.; Bedard, P.Y.; Le Talaer, J.Y.

Annales de Biologie Clinique 46(2): 123-128

1988


ISSN/ISBN: 0003-3898
PMID: 3132870
Document Number: 326202
We have compared three assays for serum galactosyltransferase activity, which use ovomucoïd, asialo agalactofetuin and free N-acetylglucosamine respectively as exogenous acceptors. A very good correlation between the three assays is obtained, for the whole range of GT activity. When the methods are compared to one another, the slopes of the regression lines are similar whether the sera are collected from healthy controls, pregnant women, or women suffering from benign gynecologic diseases or ovarian neoplasms. The methods which uses free N-acetylglucosamine as acceptor is rapid, cheaper and easier to perform.

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