Undernutrition and brain growth
Yoshioka, H.; Ochi, M.; Yoshida, A.; Takeuchi, Y.; Ishimura, K.
No to Hattatsu 20(2): 115-122
1988
ISSN/ISBN: 0029-0831 PMID: 3358875 Document Number: 324936
Effects of early undernutrition and subsequent rehabilitation on brain growth and development were investigated in mice. In M1-20 group (mice nursed in litters of 18 from day 1 to 20) the body and brain weight gains were insufficient. In M1-10 also the brain weight was not completely restored. Although in M1-5 the brain weight in adulthood was almost the same as in controls, that in M8-12 was less than in M1-10. In addition, insufficient dendritic development of cortical neurons and disturbed serotonin system were seen in severely malnourished animals.