Prenatal growth curves corrected for certain genetic and environmental factors

Kumar, R.

Journal of Tropical Pediatrics 38(5): 256-261

1992


ISSN/ISBN: 0142-6338
PMID: 1433453
DOI: 10.1093/tropej/38.5.256
Document Number: 324003
Factor analysis for non-orthogonal data was done to assess the straight and interaction effects of certain genetic and environmental factors on birth weight. While the interaction effects did not assume any significance, straight effects of gestational age, parity, mother's weight, and sex were significant in influencing the birth weight. Mother's height and socio-economic status of the family had no significant effect on birth weight. Step-up multiple regression analysis showed that contribution to the total variance explained (R-2 times 100 = 29.7 percent) in birth weight was about 15, 7, 5, and 2 percent, respectively, from gestational age, parity, mother's weight, and sex of the baby. Correction of the mean weight curve was done by successive graphic approximation method and residuals were further minimized.

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