Clinical efficacy of a Minidiab preparation (glipizide) in an acute experiment
Borisova, A.M.; Taneva, T.; Koev, D.; Georgieva, R.
Vutreshni Bolesti 27(2): 85-89
1988
ISSN/ISBN: 0506-2772 PMID: 3137730 Document Number: 322692
The hypoglycemic action of Minidiab (Glipizide) and maninil (Glibenclamide) were studied in an acute experiment. 10 patients with type 2 diabetes mellitus (6 men and 4 women, mean age 49.1 years, were examined. The blood sugar level and the insulinemia were followed up after a 10 mg morning dose of each drug. The hypoglycemic action of both drugs is identical but is reached in different ways. Minidiab has a faster, shorter but stronger insulinotropic action. Maninil exerts a better peripheral effect.