Neuroleptic malignant syndrome: a review of the Wellington experience
Maling, T.J.; MacDonald, A.D.; Davis, M.; Hawkins, T.
New Zealand Medical Journal 101(844): 193-195
1988
ISSN/ISBN: 0028-8446 PMID: 2896326 Document Number: 321356
The neuroleptic malignant syndrome is a potentially lethal complication of central dopamine antagonism. We report five cases, occurring in the Wellington region in the last 4 years. Three of the cases are reported in detail and the diagnostic difficulties and therapeutic strategies are reviewed. Particular attention is drawn to the use of the depot intramuscular phenothiazine formulations which were clearly implicated in our experience.