Malignant neuroleptic syndrome

Segado Soriano, A.; López Gonzalez-Cobos, C.; Villalba Garciá, M.V.; Gil Gómez, J.; Muiño Miguez, A.; Millan Núñez-Cortés, J.

Anales de Medicina Interna 14(5): 231-235

1997


ISSN/ISBN: 0212-7199
PMID: 9235098
Document Number: 473465
Neuroleptic Malignant Syndrome (NMS) is a rare disease characterized by hyperthermia, altered level of consciousness, autonomic dysfunction and muscular rigidity in relation to treatment with different drugs. We describe ten patients with Neuroleptic Malignant Syndrome in our Hospital. The mean age was 48 +/- 18 and females were majority (70%). Haloperidol, alone or with another farms, was relation with NMS in the 90% of the cases. Mortality became the 20% and it was relation with respiratory failure and delayed on admission in Intensive Care Unit (UCI). We remarked the importance to have a high suspicious index for attending of this disease by a precocious and intensive treatment.

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