A randomized controlled trial of valethamate bromide in acceleration of labor
Kuruvila, S.; Jasper, P.; Peedicayil, A.; Mathai, M.
International Journal of Gynaecology and Obstetrics the Official Organ of the International Federation of Gynaecology and Obstetrics 38(2): 93-96
1992
ISSN/ISBN: 0020-7292 PMID: 1356851 DOI: 10.1016/0020-7292(92)90042-hDocument Number: 320278
A randomized controlled study of valethamate bromide administered by intramuscular injection in acceleration of labor was done in 60 consecutive primigravidae and 60 consecutive multigravidae admitted in labor at 2-4 cm cervical dilatation. There was no difference observed in the rate of cervical dilatation between those who received valethamate bromide and those who received normal saline. However, maternal tachycardia was observed in significantly more women (primigravida RR 1.97, 95% CI 1.3-3.0; multigravida RR 2.16, 95% CI 1.3-3.6) who had received valethamate bromide.