Activity and tolerability of domifen bromide in patients affected by acute infectious dental diseases: a double-blind placebo-controlled trial
Scaglione, F.; Coduri, M.; Nebuloni, R.; Fraschini, F.
International Journal of Clinical Pharmacology Research 3(5): 357-361
1983
ISSN/ISBN: 0251-1649 PMID: 6381338 Document Number: 4951
Thirty-one patients (21 M and 10 F), affected by acute infectious dental disease, were treated with domifen bromide (A) or placebo (Pl). It was found that A had a beneficial effect on the results of clinical controls and reduced the need for the concomitant use of an antibiotic (p = 0.001 and p = .008 respectively). Furthermore, after two days of treatment with A, there was a significant decrease in pain and inflammation (p less than 0.01). A alone or in combination with an antibiotic elicits a good response, improves the prognosis and reduces the number of days of illness.
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