Type I like collagen appeared in vitreous disease

Hara, A.; Watanabe, T.; Namimatsu, S.

Nippon Ganka Gakkai Zasshi 92(8): 1363-1368

1988


ISSN/ISBN: 0029-0203
PMID: 3195393
Document Number: 320146
Specimens taken from 33 vitrectomy cases were examined under electron microscopy. The vitreous diseases of the 33 cases included vitreous hemorrhage, proliferative retinopathy, retinal detachment and ocular trauma. Collagen fibers in each specimen were classified into specific types. The composition of different types of collagen fibers in each vitreous membrane was evaluated. collagen resunbhng was Type2 observed in all cases of vitreous diseases. collagen resembluy Type 1 appeared only in the penetreating and perforating trauma group. Incidence of Type 1 like collagen appearance in specimens was higher in penetrating trauma than in perforating trauma. We assumed that the general wound healing response in the vitreous was carried out type 2 collagen. However in urgent situations the would healing response is carried out not only by type 2 collagen but als by type 1 collagen fiber.

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