Detection of transforming sequences in human melanomas and leukemias
Noguchi, T.; Marics, I.; Adelaide, J.; Raybaud, F.; Planche, J.; Batoz, M.; Auberts, C.; de Lapeyriere, O.; Birnbaum, D.
Cancer Detection and Prevention 12(1-6): 383-388
1988
ISSN/ISBN: 0361-090X PMID: 3052836 Document Number: 319946
DNA extracted from fresh solid human melanoma tumors and untreated acute myeloid leukemic cells was used in two assays designed to detect oncogenes, based on the transfection of murine NIH 3T3 fibroblasts followed by selection of transformed cells in low serum concentration or induction of tumors in athymic mice. Ras and non-ras oncogenes were detected.
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