Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas
Agrup, G.; Hansson, C.; Rorsman, H.; Rosengren, A.M.; Rosengren, E.
Acta Dermato-Venereologica 58(3): 270-272
1978
ISSN/ISBN: 0001-5555 PMID: 78645 Document Number: 135611
Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas. Subsequent hydrolysis of carefully washed melanoma tissue released dopa and 5-S-cysteinyldopa, indication the presence of these catechol amino acids in proteins. Cysteinyldopa-containing proteins may represent the antigens previously demonstrated in human melanomas.