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Can one increase the analgesic effect of Mobilisin ointment by iontophoresis? Placebo controlled triple cross-over double-blind study

Pavelka, K.; Pavelka, K.; Svarcova, J.; Vácha, J.; Trnavský, K.

Zeitschrift für Rheumatologie 47(4): 233-237

1988

ISSN/ISBN: 0340-1855
PMID: 3055745
Document Number: 319161
In a double-blind, three-way crossover trial, with placebo controls on 41 patients with inflammatory rheumatic disorders (mono- or oligoarticular forms), the analgesic action of Mobilisin ointment, with or without iontophoresis, was significantly stronger than after iontophoresis alone or after placebo. Iontophoresis did not potentiate the analgesic properties of Mobilisin. The pain was scored on VAS in intervals 30 min, 1, 2, 4, 6, 8 h after application. The duration of analgesic effect after Mobilisin procedures was 6.5 h on average, which was significantly longer than after iontophoresis alone or after placebo.

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